Evolution of Drug-Eluting Stents: A Biomedical Engineering Breakthrough in Cardiovascular Intervention
DOI:
https://doi.org/10.36676/urr.v12.i3.1561Keywords:
Drug-Eluting Stents, Cardiovascular InterventionAbstract
When compared to bare-metal stents, drug-eluting stents (DES) dramatically lower restenosis rates, revolutionizing interventional cardiology. With an emphasis on stent design, medication selection, and polymer coatings, this paper examines the developments in DES technology. The creation of biodegradable polymers, the optimization of medication release kinetics, and the switch from first- to second- and third-generation stents are some of the major trends identified by a systematic review of research published between 2010 and 2023. Even with these developments, problems like biocompatibility and late stent thrombosis still exist. This study emphasizes the necessity for novel materials and customized strategies to further improve the effectiveness and safety of DES.
References
https://www.sciencedirect.com/science/article/pii/S0169409X0600024X
https://www.ahajournals.org/doi/abs/10.1161/01.cir.0000078025.19258.28
https://wires.onlinelibrary.wiley.com/doi/abs/10.1002/wnan.38
https://www.sciencedirect.com/science/article/abs/pii/S0002914907016542
https://www.sciencedirect.com/science/article/pii/S1936879809006724
https://www.sciencedirect.com/science/article/pii/S0735109713041235
https://www.sciencedirect.com/science/article/pii/S0735109705027191
https://pmc.ncbi.nlm.nih.gov/articles/PMC8364397/
https://www.sciencedirect.com/science/article/pii/S1936879814011674
Image https://academic.oup.com/cardiovascres/article/119/3/631/66313
https://pmc.ncbi.nlm.nih.gov/articles/PMC6159420/
The First-Generation Drug-Eluting Stents and Coronary Endothelial Dysfunction | JACC: Cardiovascular Interventions
https://link.springer.com/article/10.1186/s13019-022-01812-y?
https://jtd.amegroups.org/article/view/5989
Cardiothoracic Surgery
Nature
Oxford Academic
ACVP Online
www.bostonscientific.com
Reuters
Health Rounds: Adaptable implant may be improvement over heart stents
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