ENERGY METABOLISM and HEPATIC ENCEPHALOPATHY
Keywords:
Glycolysis and Glucose, ENERGyAbstract
Hepatic Encephalopathy (HE) is a major and debilitating neurological disorder occurring in patients with severe liver disease, in chronic or acute forms (Williams, 1973). A serious complication of liver failure that includes a spectrum of neuropsychiatric abnormalities. The disturbances could range from little effect on mood to coma. With wide range of manifestations, HE varies in its acute and chronic forms. Chronic HE, has mild distortions during its frame which includes mood alterations, intellectual capacity decline, muscles abnormalities (Jones and Weissenborn,1997). Acute HE has a high mortality rate around 80-90% because of inter-complications developed in duration that includes brain edema, rise of intercranial pressure, causing onset of abrupt clinical manifestations like seizures, in severe cases may lead to coma (Capocaccia and Angelico, 1991).
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